Complete Acne Therapy System


5.1 Fl Oz Wash, 1.7 Fl Oz Spf, 1.4 Fl Oz Lotion

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The Complete Acne Therapy System has the power to control acne while being gentle on your skin.

Using the two leading over-the-counter acne medicines, this powerful kit contains three acne skin care products clinically shown to significantly reduce many signs of acne in just four days, including breakouts, blackheads.

Cleanse: The Skin Polishing Acne Cleanser contains Salicylic Acid, that penetrates pores as it cleanses to clear oil and impurities. Meanwhile, glycolic acid polishes by helping to sweep away roughness and dead skin. Treats acne and helps prevent future breakouts for clearer, healthier-looking skin.

Day: The Oil-Free SPF 15 Lotion (as needed) is a unique combination of SPF 15 and DermaNaturals®, an exclusive botanical complex. This sunscreen for acne-prone skin helps protect skin from the sun’s damaging UV rays.

Night: The Acne Control Lotion contains Benzoyl Peroxide acne medicine, which kills acne-causing bacteria, treats inflamed breakouts and helps prevent future acne.

  • Non-comedogenic (won't clog pores)

how to use

This complete acne therapy solution takes the dermatologist’s approach to treat your skin in one high efficacy kit. Simply cleanse and treat twice a day. It is important to use all 3 products daily and consistently to help maintain clear skin.

  • Cleanse: Skin Polishing Acne Cleanser - Wet face, Squeeze into hand. Apply to face and massage gently. Rinse thoroughly. If excessive drying or peeling occurs, reduce application to every other day.
  • Day: Oil-Free SPF 15 Lotion - Apply liberally 15 minutes before sun exposure. Reapply at least every 2 hours. Use a water resistance sunscreen if swimming or sweating. Children under 6 months of age: Ask a doctor
  • Night: Acne Control Lotion - Cleanse skin thoroughly before applying this product. Cover the entire affected area with a thin layer. If bothersome dryness or peeling occurs, reduce application to every other day. If irritation or sensitivity develops, stop use of both products and ask a doctor.

See what's inside

While Neutrogena® strives to keep ingredient lists on this website as accurate as possible, we cannot guarantee that these lists are complete, reliable, up-to-date, and error-free. Please refer to the ingredients list on the product packaging for the most accurate list of ingredients.

Acne Control Lotion

Active ingredient

Benzoyl peroxide 2.5% (Acne Medication)

Inactive ingredients

Water, Carbomer, Homopolymer Type B, Ethlhexylglycerin, Sodium Hydroxide, Chlorphenesin, Disodium EDTA, Laureth-4, Hydroxypropyl Methylcellulose

Skin Polishing Acne Cleanser

Active ingredient

Salicylic Acid 2% (Acne treatment)

Inactive ingredients

Water, Cetyl Alcohol, PPG-15 Stearyl Ether, Glycolic Acid, Glycerin, Polysorbate 60, Steareth-21, C12-15 Alkyl Lactate, Cetyl Lactate, Potassium Cetyl Phosphate, Sodium Hydroxide, Xanthan Gum, Cocamidopropyl PG-Dimonium Chloride Phosphate, Disodium EDTA, Menthol, Fragrance, Benzalkonium Chloride, Panthenol

Oil Free Moisture With Sunscreen Broad Spectrum SPF 15

Active ingredient

Avobenzone (1.5%), Octisalate (5%), Octocrylene (3%), Oxybenzone (4%) (Sunscreen)

Inactive ingredients

Water, Octyldodecyl Neopentanoate, Glycerin, Emulsifying Wax NF, Glyceryl Stearate, PEG-100 Stearate, Dimethicone, Phenoxyethanol, Ethylhexylglycerin, Caprylyl Glycol, Carbomer, Triethanolamine, Methylparaben, Disodium EDTA, Ethylene Brassylate, Dipropylene Glycol, Dimethyl Heptenal

Drug Facts


Active ingredient
Benzoyl peroxide 2.5%
Acne Medication
For the treatment of acne
Warnings: For external use only.
Do not use have very sensitive skin. are sensitive to benzoyl peroxide.
When using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time avoid unnecessary sun exposure and use sunscreen. avoid contact with the eyes, lips, and mouth. avoid contact with hair and dyed products, which may be bleached by this product. skin irritation may occur, characterized by redness, burning, itching, peeling, or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration.
Stop use and ask a doctor if irritation becomes severe.
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
cleanse skin thoroughly before applying this product
cover the entire affected area with a thin layer one to three times daily
because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor
if bothersome dryness or peeling occurs, reduce application to once a day or every other day.
wear long-sleeved shirts, pants, hats, and sunglasses
If going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor.
Inactive ingredients

Water, carbomer, homopolymer type B, ethlhexylglycerin, sodium hydroxide, chlorphenesin, disodium EDTA, laureth-4, hydroxypropyl methylcellulose


Active ingredient
Salicylic Acid 2%
Acne Treatment
For the treatment of acne.
Warnings: For external use only.
When using this product skin irritation and dryness is more likely to occur if you use another topical medication at the same time.
If irritation occurs, only use one topical medication at a time.
avoid contact with eyes. If contact occurs, rinse thoroughly with water
Keep out of reach of children. If swallowed, get medical help or contact a poison control center right away.
For sunscreen use:
Wet face
Squeeze into hands
apply to face and massage gently.
rinse thoroughly
if excessive drying or peeling occurs, reduce application to every other day
Other information
Sunburn Alert: this product contains an alpha hydroxy acid (AHA) that may increase your skin’s sensitivity to the sun and particularly the possibility of sunburn
Use a sunscreen, wear protective clothing and limit sun exposure while using this product and for a week afterwards
Store at room temperature
Inactive ingredients

Water, cetyl alcohol, PPG-15 stearyl ether, glycolic acid, glycerin, polysorbate 60, steareth-21, C12-15 alkyl lactate, cetyl lactate, potassium cetyl phosphate, sodium hydroxide, xanthan gum, cocamidopropyl PG-dimonium chloride phosphate, disodium EDTA, menthol, fragrance, benzalkonium chloride, panthenol


Active ingredients
Avobenzone (1.5%), Octisalate (5%), Octocrylene (3%), Oxybenzone (4%)
helps prevent sunburn
if used as directed with other sun protection measures (see Directions), decreases the risk of skin cancer and early skin aging caused by the sun
Warnings: For external use only.
Do not use on damaged or broken skin.
When using this product keep out of eyes. Rinse with water to remove.
Stop use and ask a doctor if rash occurs
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away
For sunscreen use:
apply liberally and evenly 15 minutes before sun exposure
reapply at least every 2 hours
use a water resistant sunscreen if swimming or sweating
Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including:
limit time in the sun, especially from 10 a.m. – 2 p.m.
wear long-sleeved shirts, pants, hats, and sunglasses
children under 6 months of age: Ask a doctor
Other information
protect this product from excessive heat and direct sun
may stain some fabrics
Inactive ingredients

Water, octyldodecyl neopentanoate, glycerin, emulsifying wax NF, glyceryl stearate, PEG-100 stearate, dimethicone, phenoxyethanol, ethylhexylglycerin, caprylyl glycol, carbomer, triethanolamine, methylparaben, disodium EDTA, ethylene brassylate, dipropylene glycol, dimethyl heptenal.


Visit or call toll-free 800-582-4048 or 215-273-8755 (collect).

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Complete Acne Therapy System is rated 4.0 out of 5 by 408.
Rated 1 out of 5 by from Hate the new formula The new formula is greasy, no longer takes off my makeup, and I'm breaking out again. Very upset thought I finally found a acne kit that worked for me then they change it.
Date published: 2017-10-11
Rated 1 out of 5 by from New Formula doesn't work The new formula does work for me. After washing my face it doesn't feel clean and leaves a greasy film. I hve to use a makeup wipe aftwsrds and I still have makeup on my face. Is there any way to buy the original formula still? I was using your product at least 9 years. it was the only product that kept me from breaking out.
Date published: 2017-10-05
Rated 1 out of 5 by from I hate the new formula! What did you do?!?! I have been using this set religiously for almost 10 years. It cleared up my skin after college after many years of struggle with acne. Within a couple days of using this new formula I have broken out worse than I ever have in the last 10 years. I am sad and feel lost because I feel like I have to start over in my search for face products. I wish I could buy the old products! Is that possible? If you bring it back, or have another product that mimics the old system, let me know. If not I am a sad, disappointed, former very loyal customer.
Date published: 2017-10-04
Rated 1 out of 5 by from This new formula breaks me out I was a very strong advocate of the Complete Acne Therapy System, after all it worked on my very oily, but dry in some places, acne prone skin. I always got compliments on my skin. One day this year I went to the drug store where I always buy the my C.A.T.S. The first thing I noticed was the cleanser did not have the beads and would not sud, no big issue i just mixed it with my Neutrogena Oil Fee Acne Wash as usual. 2nd I noticed the textrue of the Acne control was off not as firm. Finally the Lotion had this wierd smell that stopped me in my tracks. not really a terrible smell but definitely a smell. Like a not great watermelon smell. I grabbed the box and noticed the small silver tab in the corner that said new formula. I panicked buy was sure that there would be no change in my skin so I continued to use it. By day 3 my skin was covered in acne and I as not happy. I also noticed that the manufacturing place changed. Please understand that this is not the same formula and should be marketed as something totally different. Thank you for all the years of clear skin.
Date published: 2017-09-27
Rated 4 out of 5 by from It has helped so much. My face has been breaking out like crazy, especially around my cheeks and chin and I have tried so many cleansers. I've tried biore, and other neutrogena products. But this one really did its job. I stopped using other products and also stopped wearing makeup (even though it made me feel super insecure) but even after a couple of days, my acne started to clear up. It has been over a month and I only get a few pimples here and there. I also have not used makeup. Now I'm working on clearing up my blemishes. I hope this helps you too.
Date published: 2017-09-06
Rated 2 out of 5 by from Causing dryness Been using it for two weeks now and my skin is so dry it looks like I have exzema especially around my eyes. Have tried Neutrogena naturals facial cleanser and multivitamin nourishing moisturizer before this and that did not help either. I am sure there must be something from Neutrogena if you can help recommend something? I am desperate my pimple breakout hurts so bad never had any acne products before. While I am recommending this to others it may not work for everyone.
Date published: 2017-09-01
Rated 1 out of 5 by from I HATE IT THE NEW FORMULA I am suffering from bad acne at the moment but my go to is always this. I stopped using this because I had been trying to cleanse my face from any products because it was my fault to use different products simultaneously. ANYWAYS, the new formula is awful and made my skin worse. BRING BACK THE ORIGINAL OR JUST TAKE OUT THE GLYCOLIC ACID. DOES NOT COMBINE WITH SALICYLIC ACID WELL.
Date published: 2017-08-14
Rated 5 out of 5 by from I am very happy when I found this kit, Sun Screen I love that this kit includes Moisteriser and Sun Screen! I use daily and it works well!
Date published: 2017-07-31
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